In 2023, One Piece fans were treated to an exciting end to the year with the release of chapter 1103. This chapter was a gem in the Egghead Island arc, taking readers back to the fight on Egghead Island full of
Author Eiichiro Oda also surprised everyone by revealing the secret of the mysterious sapphire scab disease.
What is sapphire scab?
First seen in Ginny during Kuma’s flashback, the sapphire scab disease turns out to have tragic origins.
The disease manifests itself as blue scales that spread throughout the body and is fatal.
This disease becomes worse when exposed to natural light, it accelerates the death process.
Sapphire scab disease is mentioned again in One Piece chapter 1103, as a medical mystery in the world of the series.
How is Sapphire scab created?
It turns out that Sapphire scab is the result of failed experiments.
The origin of sapphire scab disease has finally been revealed.
Saturn’s ability to cause illness may be related to his scientific knowledge or his Devil Fruit.
Amber Lead Poisoning Syndrome (which Law suffers from), like Sapphire scales are based on a stone and mysteriously appear in the One Piece world.
Aurora 
Naomi 
Caroline